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Dermorphin TFA

CAS No. 78331-26-7

Dermorphin TFA( —— )

Catalog No. M21054 CAS No. 78331-26-7

Dermorphin TFA is a new class of opioids-like peptides.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Dermorphin TFA
  • Note
    Research use only, not for human use.
  • Brief Description
    Dermorphin TFA is a new class of opioids-like peptides.
  • Description
    Dermorphin TFA is a new class of opioids-like peptides.
  • In Vitro
    Dermorphin, a peptide isolated from the skin of Phyllomedusa frogs and the peptide receptor (NOP) component by the endogenous agonist nociceptin/orphanin FQ (N/OFQ). In displacement binding studies at CHOhMu, Dermorphin and DeNo displac the binding of [3H]-DPN in a concentration dependent and saturable manner. Dermorphin displays an affinity of 7.17, while N/OFQ fails to displace [3H]-DPN at the Delta receptor. Dermorphin and DeNo stimulate the binding of GTPγ[35S] in a concentration dependent and saturable manner at the Mu receptor.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    78331-26-7
  • Formula Weight
    916.89
  • Molecular Formula
    C42H51F3N8O12
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(N)=O.O=C(O)C(F)(F)F
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Castiglione R D Faoro F Perseo G et al. SYNTHESIS OF DERMORPHINS A NEW CLASS OF OPIATE-LIKE PEPTIDES[J]. Chemical Biology & Drug Design 1981 17(2):263-272.
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